Biomedical Research Department


The New KKMC-CHR Biomedical Research Facility (BRF) at KFSH-D

The mission of the Biomedical Research Facility is to establish a multidisciplinary and highly competitive applied research program in the fields of Cancer Research, Transplantation, Neurosciences and Obesity/Diabetes. The research facility will integrate several scientific disciplines such as Immunology, Stem Cells Biology, Cellular Therapy, Cancer Vaccine, Molecular Diagnosis, Molecular Targeting and Molecular Biology with the ultimate objective of developing preventive and therapeutic strategies to control and/or treat cancer, neurological disorders, obesity/diabetes and to develop immunomodulatory protocols to preserve organs/tissues/cells in transplantation without compromising immune responses to infection. The latest technologies will be used in order to achieve this mission. Also in parallel, the research activities at the BRF will be supported by the creation of a Tissue/Biobank Core Facility to provide high quality human biomaterials in a manner that is well documented, safe, efficient and ethically sound, to all interested investigators who have received approval from KFSH-D and other Institutional Review Board (IRB) for academic testing and research. In addition, the Tissue/Biobank Core Facility will acquired some human and animal cell lines from commercial and private sources that can be expanded and maintained at the facility for investigator’s use. Along with its research/scientific activities, the BRF will be actively involved in coordination with all the clinical laboratories and departments at KFSH-D in disseminating knowledge and technology transfer by creating and facilitating other activities such as collaboration, training and education, organization of workshops and meetings at national, regional and international levels to integrate science with the clinic.

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Cancer Research Program:
     1. Immunology (Targeted Therapy, Cellular Therapy, Vaccine and Immunotherapy)
     2. T-Cell Therapy for Viral Infections Following Bone Marrow/Stem Cell Transplantation
     3. Genetics and Functional Genomics
Transplantation Program:
     1. Immune Regulation (Regulatory T cells: Tregs)
     2. Mesenchymal stem cells (MSC)
     3. Cellular Therapy against viral infection
Neurosciences Program:
      1. Immune Regulation in Multiple Sclerosis (MS) using Regulatory T cells (Tregs)
      2. Obesity/Diabetes Program:
      3. Investigation Of The Immunological Basis Underlying Childhood Obesity In The Eastern Province Of Saudi Arabia

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Acquired Technologies to achieve the BRF goals
We are using the most innovative scientific and technological tools such as Functional Genomics, Next Generation Sequencing Technologies, Microarray Technology, Multiplexing Technology and Flow Cytometry/Cell Sorting technologies to achieve our goal.